Figure 5

Progesterone and estradiol production is modified upon H-Pgds enzymatic inhibition. (A), serum progesterone levels. (B), serum estradiol levels were measured by Elisa on extracted sera. Bars represent the average of twenty animals (n = 20 for untreated mice and n = 20 for HQL-79 treated mice). HQL-79 treatment induces a 50% decrease of progesterone production and a 50% increase of estradiol production. * represents significant differences P < 0.05, compared to untreated ovaries (-HQL-79).