Fig. 6

ELAVL2 structure complexed with ZINC03830554. (A) A cartoon depiction of the ELAVL2 complex. (B) A zoomed surface illustration of ELAVL2 and ZINC03830554 is shown as sticks. (C) A close-up of the substrate binding pocket, which shows the critical amino acid residues of ELAVL2 interacting with the inhibitor compound ZINC03830554. (D) Surface depiction of ELAVL2’s preserved substrate-binding pocket