Fig. 1
From: Ovarian Hyperstimulation syndrome combined with hypothyroidism: a comprehensive review
The types, population, characteristic and mechanisms of OHSS and HT. →:promoting; —|:inhibiting; ①:TSH exhibits weak FSH activity, which can activate the FSH-R; ②Patients with HT are more inclined to produce E3, and E3 has a weaker inhibitory effect on the release of gonadotropins compared to E2, leading to excessive release of gonadotropins; ③Elevated serum E2 levels can increase serum TBG levels; high levels of TBG bind more FT4, resulting in decreased serum FT4 and increased serum TSH levels