Table 2 Case reports of sOHSS combined with HT in naturally pregnant women
From: Ovarian Hyperstimulation syndrome combined with hypothyroidism: a comprehensive review
No | Age | Pregnancy | TSH | FT4 | FT3 | LH | FSH | β-hCG | E2 pg/ml | CA125 | Ultrasonography Report (bilateral ovarian size) | Treatment | The duration of returning to normal | Successful delivery gestational weeks |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nappi, Di Naro [44] | 34 | 12w | > 350 μU/ml | Low | Low | 0.5 mIU/ml | 0.6 mIU/ml | 12,8461 mIU/ml | 9150 | – | Diameter:13 cm, Diameter: 11 cm | LT4 replacement treatment | 2 weeks | 38 weeks |
Cardoso, Graça [45] | 25 | 12w | 210 mIU/mL | 0.2 ng/dL | 1.3 pg/mL | – | – | 15,890 mIU/mL | – | 74.5 U/mL | 16 × 15 cm; 16 × 13 cm | LT4 replacement treatment | 24 weeks gestation | 28 weeks |
Borna and Nasery [47] | 30 | 20w | >400μU/mL | 0.4 ng/dL | 1.1 pg/mL | – | – | – | – | 39 U/mL | 20 × 16 cm; 16 × 10 cm | LT4 replacement treatment | 10 weeks after delivery | 38 weeks |
Edwards-Silva, Han [42] | 30 | 10w | 41.7 mU/L | – | – | – | – | 291,206 mIU/mL | – | 901 U/mL | 10 × 14 × 7 cm; 10 × 12 × 8 cm | LT4 replacement treatment | – | 34 weeks |
Lussiana, Guani [46] | 29 | 22w | 5.92 mU/l | Normal | Normal | Normal | Normal | High | High | – | 20 × 11 cm; 16 × 12 cm | – | 3 weeks after abortion | abortion |
Akbay, Uzunçakmak [48] | 21 | 10wa | 8.75 IU/mL | – | – | – | – | High | – | 146.8 IU/ml | 13 × 8 cm | LT4 replacement treatment | 3 weeks after delivery | – |
23 | 12wa | 2.16 IU/mL | – | – | – | – | High | – | 289 IU/ml | 1.3 × 7 cm; 11 × 7 cm | LT4 replacement treatment | 6 weeks after delivery | 38 weeks | |
Dieterich, Bolz [43] | 26b | 12w | 3.73mIU/l | 13.9 pmol/l | 4.8 pmol/l | – | – | 118,665 IU/l | – | – | – | Diuresis; Fluid drainage | – | Termination of pregnancy (15 weeks) |
26b | 10w | 5.51mIU/l | 15.3 pmol/l | 3.8 pmol/l | – | – | 147,688 IU/l | – | – | 6 × 7 cm; 5 × 7 cm | LT4 replacement treatment | 18 weeks gestation | 39 weeks | |
Delabaere, Tran [49] | 23 | 12w | High | Low | Normal | Normal | Normal | Match | – | – | 17 × 10.2 cm; 14.2 × 7 cm | LT4 replacement treatment | 3 months | 39 weeks |
Sridev and Barathan [50] | 22 | 9w | 150 μIU/ml | – | – | – | – | 181,264.20mIU/ml | – |  | 10 × 8 cm; 8 × 6 cm | LT4 replacement treatment | 20 weeks gestation | 39 weeks |
SEETHAPATHY [51] | 20 | 14w | 222mIU/ml | 0.07 ng/dl | < 0.26 g/ml | – | – | 1,36,776 mIU/ml | – | – | 15 × 9 × 13 cm; 12 × 8 × 14.6 cm | LT4 replacement treatment | 4 months after abortion | Abortion |
Oliveira, Innecco Arêas [52] | 32 | 13w | 100 mU/L | 0.25 ng/dl | – | – | – | – | – | 125 56 U/ml | 9.3 × 6.3 × 5.9 cm; 10.6 × 10.0 × 7.1 cm | LT4 replacement treatment | 8 months after delivery | 37 weeks |
Alzebidi, Almushri [53] | 27 | 10w | 123mIU/ml | Low | – | < 3 IU/l | 11.92mIU/ml | 23150mIU/ml | 758.93 | 11 IU/ml | 10 × 9.7 × 11.7 cm; 7.5 × 10.5 × 10.3 cm | LT4 replacement treatment | 3 months after delivery | – |
Guerra, Marado [54] | 22 | 9w | 515 IU/mL | 0 | – | – | – | – | – | 1045 U/mL | 15 × 14 × 16.6; 15× 8.2 × 18.3 cm | LT4 replacement treatment | 3 months after abortion | Termination of pregnancy (10 weeks) |