Fig. 1

C-Myb and cisplatin resistance. C-Myb levels were detected in parental and cisplatin resistant ES2 (A) and A2780 (B) cells. Cell proliferation, to assess cytotoxic effects of increasing cisplatin, was assessed in parental and cisplatin resistant ES2 (C) and A2780 (D) cells with an additional silencing of c-Myb in resistant cells (ES2C-si / A2780C-si). The presented results are representative of at least 3 different repeats with triplicate samples in each repeat. #p<0.05, compared to control. *p<0.05, compared to resistant cells without silencing of c-Myb.