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Fig. 5 | Journal of Ovarian Research

Fig. 5

From: Cyclophosphamide induces ovarian granulosa cell ferroptosis via a mechanism associated with HO-1 and ROS-mediated mitochondrial dysfunction

Fig. 5

HO-1 Knockdown reduced the effect of CTX in GCs. (A) qPCR and (B) western blot analysis were used to measure the transfection efficiency and GPX4 expression of si-HO-1 in COV434 and KGN cells. (C) Morphological changes and (D) cell viability were examined in COV434 and KGN cells after HO-1 knockdown. Scale bars = 100 μm. **p < 0.01 and ****p < 0.0001 for the indicated comparisons

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Journal of Ovarian Research

ISSN: 1757-2215

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