Fig. 1

CENPO is upregulated in OV and the identification of lentivirus knockdown inefficiency. (A) CENPO mRNA expression levels in 426 ovarian cancer tissues and 88 normal tissues according to the TCGA and GTEx dataset (P < 0.0001). (B) mRNA expression levels in 5 ovarian cancer cell lines and 1normal ovarian cell lines. (C) Fluorescent image of SK-OV-3 and ES-2 cells infected with lentivirus. D) Comparison of mRNA expression abundance between shCtrl and shCENPO group in two cell lines. (E) Comparison of protein expression between shCtrl and shCENPO. Each western blot experiment was repeated three times. (Significant differences between two groups were analyzed using Student’s t-test. Significance was indicated as follows: p ≤ 0.05 (*); p ≤ 0.01 (**); p ≤ 0.001 (***); p ≤ 0.0001 (****))