Fig. 5

Analysis of significant difference between shCtrl group and shCENPO group after transfection of SK-OV-3 with CENP-O shRNA lentivirus. (A) Hierarchical clustering assay of the control and the CENP-O shRNA groups were performed, Red/green indicates a relatively upregulated/downregulated expression level of genes, black indicates that there is no significant change in gene expression, and gray indicates that the gene signal intensity was not detected. (B) Scatter plot of the control and the CENP-O shRNA groups drawn based on the significant difference analysis. The red dots outside the interval represent probe sets that are relatively upregulated in the KD group, while the green dots represent probe sets that are relatively upregulated in the NC group. (C) Volcano Plot of the control and the CENP-O shRNA groups drawed based on the significant difference analysis. The red dots represent differentially expressed genes that were screened based on the criteria of |Fold Change|≥1.3 and FDR < 0.05, while the gray dots represent other genes with no significant differences in expression