Fig. 7

Selection and validation of downstream genes. (A) RB1, MMP9, BMP4, DAPK1, FGFR3, ITGAV, JAK2, IGFBP1, AKT2, PABPN1 were selected based on IPA analysis and verified using qPCR. (B) JAK2, EZH2, RB1, AKT2, MMP9, and MKP-1 were chosen for Western-blot validation. (C) The gray analysis results in Figure B. (Significant differences between two groups were analyzed using Student’s t-test. Significance was indicated as follows: p ≤ 0.05 (*); p ≤ 0.01 (**); p ≤ 0.001 (***); p ≤ 0.0001 (****))