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Fig. 4 | Journal of Ovarian Research

Fig. 4

From: Genomic alteration discordance in the paired primary-recurrent ovarian cancers: based on the comprehensive genomic profiling (CGP) analysis

Fig. 4

Identifying cancer driver genes and pathways among all somatic mutations detected in a cohort of the primary and recurrent tumors. (A) Comparison and identification of cancer drivers in the paired primary-recurrent tumors. (B) Mutational analysis of candidate cancer driver genes (NOTCH1, MSH2, and MSH6) in the primary and recurrent tumors. (C) Enrichment analysis of the mutated genes identified in genomes of the primary and recurrent tumors for 10 TCGA canonical signaling pathway

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Journal of Ovarian Research

ISSN: 1757-2215

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