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Table 1 Baseline characteristics of the enrolled patients in the study

From: Genomic alteration discordance in the paired primary-recurrent ovarian cancers: based on the comprehensive genomic profiling (CGP) analysis

Characteristics

Number (%)

Total number of the enrolled patients

20 (100)

Age at diagnosis, Median (range), years-old

48 (45–68)

FIGO Staging Classification

 

 I

 II

 III

 Unknow

1 (5.0)

4 (20.0)

13 (65.0)

2 (10.0)

Tumor histology

 

 Serous

 Others

17 (85.0)

3 (15.0)

Neoadjuvant treatment

 

 Yes (PTX plus CBP)

 No

7 (35.0)

13 (65.0)

Targeted molecular therapy (Olaparib)

 

 Olaparib

 No

5 (25.0)

15 (75.0)

First-line chemotherapy

 

 PTX plus CBP

 PTX plus DDP

13 (65.0)

3 (15.0)

 Other platinum-containing regimens

4 (20.0)

Operation interval, Median (range), months

29.5 (13.5–60.0)

Platinum-free interval (PFI), Median (range), months

15.0 (6.0-36.5)

Follow-up, Median (range), months

 Live

 Death

 Lose

63.0 (34.0-108.0)

12 (60.0)

7 (35.0)

1 (5.0)

  1. FIGO, International Federation of Gynecologists and Obstetricians. PTX, Paclitaxel. CBP, Carboplatin. DDP, Cisplatin/ cis-diamminedichloro-platinum
  2. Platinum-free interval (PFI), which is calculated from the last platinum-based chemotherapy to the time of recurrence; Operation interval, refers to the interval between the PDS or NAC/IDS and the secondary debulking surgery