Fig. 4

Circ_0043532 promoted CYP19A1 expression by sponging miR-1270. A The Venn diagram of potential target genes of miR-1270 predicted by miRWalk, RNA22, TargetScan, RNAhybrid and miRanda. B Relative expression levels of CYP19A1 quantified by qRT-PCR between the PCOS and non-PCOS groups. C Effects of miR-1270 mimics or inhibitor and pEX-circ_0043532 on the expressions of CYP19A1 were determined by RT-qPCR. D-E Western blot assay was performed to detect the expression of CYP19A1 after transfected with miR-1270 mimic or inhibitor and its NC as well as pEX-circ_0043532. The data are presented as the means ± SD. * indicates p < 0.05, ** indicates p < 0.01