Fig. 2

Changes of ovarian function after transplantation. A Histological analysis of ovaries was performed by HE staining. Scale bar: 500 μm. B The number of follicles at different developmental stages in each group was counted at 2 and 4 weeks after implantation. Serum levels of E2, FSH, AMH (C) and the percentage of irregular estrous cycles (D) were evaluated at 2 and 4 weeks after graft transplantation. E Changes of body weight were assessed before and after treatment. The red dash line indicates the time points of treatment. (* versus the normal group, # versus the POI group, & comparison between two groups; *, #, & P < 0.05; **, ##, && P < 0.01; ***, ###, &&& P < 0.001; n = 6 per group)