Fig. 8

Oxidative Stress Parameters in Granulosa Cells following treatment with MenSCs and MenSCs- EXO. a MDA concentrations in culture medium of different groups showing higher levels in PCOS compared to control, with reductions following treatment with MenSCs and MenSCs-EXO. Data are presented as mean ± standard deviation. a = P ≤ 0.016 vs PCOS; b = P ≤ 0.015 vs PCOS; c = P ≤ 0.003 vs Control. b SOD Activity in cell lysates, showing a significant increase in MenSCs-treated cells compared to PCOS, while MenSCs-EXO treatment did not significantly change SOD activity. Data are presented as mean ± standard deviation. a = P ≤ 0.011 vs PCOS; b = P ≤ 0.001 vs Control; c = P ≤ 0.002 vs Control and d = P ≤ 0.0001 vs Control