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Fig. 4 | Journal of Ovarian Research

Fig. 4

From: Bone marrow mesenchymal stem cells expressing Neat-1, Hotair-1, miR-21, miR-644, and miR-144 subsided cyclophosphamide-induced ovarian insufficiency by remodeling the IGF-1–kisspeptin system, ovarian apoptosis, and angiogenesis

Fig. 4

Effect of BM-MSCs transplantation on mRNA expression of IGF-1/HPG axis of the POI rats (AF). A. hypothalamic mRNA IGF-1, B. hypothalamic mRNA Kiss-1, C. hypothalamic mRNA Kiss-r1, D. hypothalamic mRNA GnIH-1, E. hypothalamic mRNA GnRH, and F. hypothalamic mRNA GnRHr. The values represent the average of 6 to 8 rats in each group ± SEM *p < 0.05, **p < 0.01, ****p < 0.0001

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