Table 1 Characteristics of baseline and controlled ovarian hyperstimulation cycles among Poseidon Group 3 and Group 4 patients grouped by DFP

N

376

217

371

192

Female age (years)

30.22 ± 2.99

28.77 ± 3.06

0.084

39.20 ± 3.21

38.99 ± 3.44

0.462

Male age (years)

31.29 ± 3.87

31.23 ± 4.12

0.860

40.5 ± 5.45

39.7 ± 5.74

0.105

Infertility duration (years)

3.15 ± 2.48

3.00 ± 2.13

0.446

4.21 ± 4.04

3.79 ± 3.59

0.221

Infertility type (%)

0.606

0.308

   Primary

191/376 (50.8)

115/217 (53.0)

54/371 (14.6)

22/192 (11.5)

   Secondary

185/376 (49.2)

102/217 (47.0)

317/371 (85.4)

170/192 (88.5)

BMI (kg/m²)

22.74 ± 3.38

22.33 ± 3.22

0.154

22.90 ± 2.87

23.07 ± 3.10

0.497

Basal FSH (IU/L)

9.28 ± 2.98

9.01 ± 2.34

0.335

9.40 ± 2.65

9.45 ± 2.88

0.850

Basal LH (IU/L)

3.78 ± 1.80

3.67 ± 1.51

0.449

3.80 ± 1.81

4.00 ± 2.51

0.282

AMH (ng/mL)

1.03 ± 1.02

1.06 ± 1.23

0.759

0.97 ± 0.78

0.87 ± 0.75

0.171

AFC

6.18 ± 3.16

5.82 ± 2.99

0.178

5.41 ± 2.50

5.66 ± 2.72

0.300

Total Gn dose (IU)

2461.90 ± 578.86

2417.67 ± 603.31

0.378

2500.27 ± 535.38

2451.43 ± 512.57

0.298

Duration of Gn (day)

9.01 ± 1.53

8.82 ± 1.66

0.158

8.74 ± 1.58

8.60 ± 1.72

0.363

Total GnRH-ant dose (IU)

0.74 ± 0.36

0.71 ± 0.39

0.365

0.75 ± 0.33

0.77 ± 0.38

0.702

Duration of GnRH-ant (day)

3.53 ± 1.28

3.50 ± 1.55

0.820

3.53 ± 1.26

3.53 ± 1.40

0.980

E2 on trigger day (pg/mL)

1999.60 ± 1100.86

2062.36 ± 1002.98

0.490

1821.57 ± 1019.90

2043.10 ± 1122.05

0.019

P on trigger day (ng/mL)

0.98 ± 0.50

1.00 ± 0.47

0.737

1.00 ± 0.70

1.00 ± 0.72

0.273

LH on trigger day (IU/L)

3.26 ± 2.10

3.20 ± 2.03

0.730

3.82 ± 2.75

3.57 ± 2.19

0.926

Trigger drugs (%)

0.085

0.538

   HCG

5/376 (1.3)

7/217 (3.2)

7/371 (1.9)

2/192 (1.0)

   GnRHa

3/376 (0.8)

5/217 (2.3)

3/371 (0.8)

3/192 (1.6)

   HCG + GnRHa

368/376 (97.9)

205/217 (94.5)

361/371 (97.3)

187/192 (97.4)

Insemination Method (%)

0.891

0.799

   IVF

278/375 (74.1)

157/216 (72.7)

230/370 (62.2)

120/192 (62.5)

   ICSI

91/375 (24.3)

56/216 (25.9)

136/370 (36.8)

71/192 (37.0)

   IVF + Rescue ICSI

6/375 (1.6)

3/216 (1.4)

4/370 (1.1)

1/192 (0.5)

Sperm density

6.84 ± 2.35

6.67 ± 2.40

0.406

6.69 ± 2.49

6.51 ± 2.58

0.449