Fig. 2

Co-expression analysis between stage-specific lncRNAs and mRNAs. A. Heatmap showing the expression pattern of stage-specific lncRNAs in granulosa cells across five stages of folliculogenesis. The stages of follicular development are presented along with the x-axis. The relative gene expression level from low to high is presented as the color scale from blue to red, respectively. B. Top 5 representative GO terms (molecular function) of mRNAs co-expressed with stage-specific lncRNAs at different stages. The row-scaled significance (-log₁₀corrected P-value) from low to high is presented as the color scale from blue to red, respectively. C-G. Network diagram identifying the hub lncRNA and co-expressed gene connections among five different developmental stages, primordial follicle (C), primary follicle (D), secondary follicle (E), antral follicle (F), preovulatory follicle (G)