Fig. 4

Afamin protein inhibits TP-induced apoptosis in KGN cells. (A) Flow cytometry analysis suggests that afamin can reduce TP-induced apoptosis in KGN cells. (B) Afamin decreased caspase-3 activity in TP-treated KGN cells. (C-D) Afamin protein reduced TP-induced apoptosis in KGN cells by increasing BCL-2 mRNA expression and decreasing BAX mRNA expression. The experiment was repeated for three times, results are expressed as mean ± standard deviation, *P < 0.05