Table 3 Results of the subgroup analysis of the serum hormones Meta-analyses based on EV source and administration route

Serum FSH

E-AFMSC

6 (1)

0.53

(-1.10, 2.16)

Intra-ovarian

106 (7)

-1.20

(-4.86, 2.47)

97.32%

H-AFMSC

40 (2)

0.71

(-14.83, 16.24)

H-BMSC

6 (1)

-0.97

(-2.66, 0.72)

H-cMSC

12 (1)

-3.44

(-5.27, -1.617)

Intraperitoneal

44 (3)

-3.03

(-6.71, 0.64)

94.56%

H-UCMSC

156 (11)

-4.01

(-6.13, -1.89)

iPSC-MSCs

12 (1)

-2.44

(-5.54, -2.17)

M-BMSC

20 (1)

-2.07

(-3.16, -0.99)

Intravenous

118 (8)

-3.51

(-5.64, -1.38)

92.76%

Menstrual blood

16 (1)

-1.26

(-2.34, -0.19)

H-AFMSC

40 (2)

0.71

(-14.83, 16.24)

Serum AMH

H-BMSC

6 (1)

1.37

(-0.41, 3.15)

Intra-ovarian

116 (7)

4.07

(1.74, 6.39)

93.57%

H-cMSC

12 (1)

3.15

(1.41, 4.90)

H-UCMSC

128 (9)

3.93

(2.10, 5.77)

iPSC-MSCs

12 (1)

2.26

(0.81, 3.71)

Intraperitoneal

44 (3)

4.09

(-2.04, 10.22)

97.95%

M-AFMSC

16 (1)

1.32

(0.24, 2.40)

M-BMSC

20 (1)

1.79

(0.76, 2.83)

Menstrual blood

16 (1)

1.51

(0.40, 2.62)

Intravenous

90 (6)

2.70

(1.90, 3.49)

62.53%

H-AFMSC

40 (2)

7.67

(3.92, 11.42)

Serum E2

H-cMSC

12 (1)

6.34

(3.53, 9.14)

Intra-ovarian

120 (8)

4.02

(1.70, 6.33)

93.72%

H-UCMSC

170 (12)

3.0

(1.85, 4.14)

iPSC-MSCs

12 (1)

2.14 (0.72, 3.56)

M-BMSC

20 (1)

1.23

(0.28, 2.19)

Intraperitoneal

44 (3)

3.59

(-1.98, 9.16)

0%

H-BMSC

16 (2)

2.93

(1.51, 4.33)

Menstrual blood

16 (1)

1.41

(0.31, 2.50)

H-AFMSC

48 (3)

6.69

(1.28, 12.13)

Intravenous

136 (10)

2.70

(1.90, 3.49)

7%

E-AFMSC

6 (1)

2.2

(0.17, 4.22)