Fig. 1
From: Neoadjuvant chemotherapy induces phenotypic mast cell changes in high grade serous ovarian cancer
Intratumoral stromal and intraepithelial mast cells are upregulated following chemotherapy exposure. (A) Representative images of hematologic mast cell staining in 36 matched pre- and post-NACT HGSOC patient tumors. Mast cells were depicted by a bright blue stain, while eosinophils were stained bright red and nuclei of cells a dull blue. Average number of positive (B) total and (C) intraepithelial and stromal mast cells pre- and post-NACT. Statistically significant differences determined by Student T-test. NACT, neoadjuvant chemotherapy, *p < 0.05, as indicated