Fig. 9

PPT2 reduced proliferation and invasion of OC cells. (A-B) Stable overexpression of PPT2 in OVCAR3 and A2780 cells. The expression of PPT2 was verified at both mRNA and protein levels. (C) Overexpression of PPT2 impaired the colony-forming ability of OVCAR3 cells. (D) Overexpression of PPT2 significantly reduced the proliferation rate of OVCAR3 cells. (E) Transwell assay results showed that overexpression of PPT2 could significantly decreased the invasion of OVCAR3 cells. (F) Overexpression of PPT2 impaired the colony-forming ability of A2780 cells. (G) Overexpression of PPT2 significantly reduced the proliferation rate of A2780 cells. (H) Transwell assay results showed that overexpression of PPT2 could significantly decreased the invasion of A2780 cells. * p < 0.05, ** p < 0.01, and *** p < 0.001