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Table 2 Comparison of pre- and post-intervention serum levels of OS markers and inflammatory cytokines between AST and placebo groups

From: Astaxanthin improves assisted reproductive technology outcomes in poor ovarian responders through alleviating oxidative stress, inflammation, and apoptosis: a randomized clinical trial

 

AST (n = 26)

  

Placebo (n = 25)

   

Variables

Pre-intervention serum levels

Post-intervention serum levels

Paired P-value

Pre-intervention serum levels

Post-intervention serum levels

Paired P-value

P-value between groups

SOD (U/ml)

14.97 ± 2.26

16.26 ± 2.22

0.013*

15.28 ± 2.01

14.59 ± 3.59

0.351

0.027*

TAC (µmol/L)

892.50 ± 81.77

910.05 ± 92.56

0.030*

918.73 ± 127.35

889.06 ± 203.20

0.468

0.246

MDA (µmol/L)

16.82 ± 1.22

16.19 ± 1.27

0.005*

16.74 ± 1.44

16.43 ± 1.64

0.135

0.261

Il-6 (pg/ml)

1.74 ± 0.33

1.25 ± 0.32

0.000*

1.61 ± 0.33

1.67 ± 0.30

0.098

0.000*

Il-8 (pg/ml)

14.62 ± 1.87

13.38 ± 1.65

0.001*

14.58 ± 2.22

14.28 ± 2.55

0.323

0.035*

VEGF (pg/ml)

13.20 ± 2.96

12.37 ± 2.87

0.002*

12.71 ± 3.19

12.43 ± 3.20

0.123

0.071

  1. AST Astaxanthin group, SOD superoxide dismutase, TAC total antioxidant capacity, MDA malondialdehyde, IL-6 interleukin 6, IL-8 interleukin 8, VEGF vascular endothelial growth factor. Table values represent mean ± SD. Statistical significance is denoted by a P-value of less than 0.05 (*P < 0.05)