Fig. 2

Transcriptomic analysis of follicular fluid extracellular vesicles in the PCOS and Control groups. A PCA analysis was performed for all miRNAs expressed in the follicular fluid extracellular vesicles, with each data point representing one sample. B Volcano map of differentially expressed miRNA. C Correlation between changes in the expression of miRNA-seq (Y-axis) and qPCR (X-axis). D Heat maps of differentially expressed miRNAs. The color indicates relative abundance: red indicates increased levels and blue indicates decreased levels. E GO (gene ontology) analysis and KEGG enrichment analysis of miRNAs with different expressions. The color of the dots indicates upregulation or downregulation, and the size of the dots indicates the number of genes