Fig. 3
From: MSCs–derived EVs protect against chemotherapy-induced ovarian toxicity: role of PI3K/AKT/mTOR axis
Representative photomicrographs of H&E-stained sections: a, b) Group I: Ovarian follicles (F) in various stages of development, and blood vessels (bv). c, d) Group II: extensive atresia of the follicles, with shrunken darkly stained nuclei (A), dilated congested blood vessels (bv), areas of hemorrhage (H), and degenerated follicles (D). e, f) Group III: Normal ovarian architecture, with developing follicles (F), blood vessels (bv), and corpus luteum (CL), g, h and i, j) Group IV and V: Fewer atretic follicles (A) in both groups with more numerous developing follicles (F) in Group IV. Persistent dilated congested blood vessels (bv) are noticed in both groups. k) Histogram demonstrating ovarian follicle count