Table 2 EGFR expression features in OC patients (420 cases)
Characteristics | N (%) | EGFR expression [N (%)] | χ2 | p value | |
|---|---|---|---|---|---|
Low (H-score ≤ 96.83) | High (H-score > 96.83) | ||||
Age at diagnosis (years) | Â | Â | Â | 2.089 | 0.148 |
  ≤ 50 | 149 (35.5) | 80(53.7) | 69(46.3) |  |  |
  > 50 | 269 (64.0) | 164(61.0) | 105(39.0) |  |  |
  Unknown | 2 (0.5) |  |  |  |  |
 Menopause |  |  |  | 0.954 | 0.329 |
  No | 150 (35.7) | 84(56.0) | 66(44.0) |  |  |
  Yes | 256 (61.0) | 156(60.9) | 100(39.1) |  |  |
  Unknown | 14 (3.3) |  |  |  |  |
Histological subtypes | Â | Â | Â | 7.106 | 0.008* |
 Serous | 371 (88.3) | 209 (56.3) | 162 (43.7) |  |  |
 Nonserous | 44 (10.5) | 34 (77.3) | 10 ((22.7) |  |  |
  Unknown | 5 (1.2) |  |  |  |  |
 FIGO stage |  |  |  | 2.706 | 0.439 |
  I | 43 (10.2) | 22 (51.2) | 21 (48.8) |  |  |
  II | 34 (8.1) | 23 (67.6) | 11 (32.4) |  |  |
  III | 291 (69.3) | 172 (59.1) | 119 (40.9) |  |  |
  IV | 18 (4.3) | 9 (50.0) | 9 (50.0) |  |  |
  Unknown | 34 (8.1) |  |  |  |  |
Histological grade | Â | Â | Â | 13.344 | 0.001* |
  Grade 1 | 24 (5.8) | 6 (25.0) | 18 (75.0) |  |  |
  Grade 2 | 17 (4.0) | 13 (76.5) | 4 (23.5) |  |  |
  Grade 3 | 332 (79.0) | 197(59.3) | 135 (40.7) |  |  |
  Unknown | 47 (11.2) |  |  |  |  |
Lymph node metastasis | Â | Â | Â | 0.106 | 0.744 |
  Negtive | 136 (32.4) | 81(59.6) | 55(40.4) |  |  |
  Positive | 76 (18.1) | 47(61.8) | 29(38.2) |  |  |
  Unknown | 208 (49.5) |  |  |  |  |
 Ascites (mL) |  |  |  | 1.503 | 0.220 |
  < 500 | 87 (20.7) | 46 (52.9) | 41(47.1) |  |  |
  ≥ 500 | 213 (50.7) | 129 (60.6) | 84(39.4) |  |  |
  Unknown | 120 (28.6) |  |  |  |  |
Preoperative CA125 (U/ml) | Â | Â | Â | Â | Â |
  < 35 | 28 (6.7) | 17(60.7) | 11(39.3) | 0.091 | 0.763 |
  ≥ 35 | 372 (88.5) | 215(57.8) | 157(42.2) |  |  |
  Unknown | 20 (4.8) |  |  |  |  |
Residual tumor size (cm) | Â | Â | Â | Â | Â |
  ≤ 1 | 137 (32.6) | 67(48.9) | 70(51.1) | 14.266 | 0.000* |
  > 1 | 59 (14.1) | 46(78.0) | 13(22.0) |  |  |
  Unknown | 224 (53.3) |  |  |  |  |
Platinum resistance | Â | Â | Â | Â | Â |
  No | 91 (21.7) | 44(48.4) | 47(51.6) | 0.782 | 0.377 |
  Yes | 35 (8.3) | 20(57.1) | 15(42.9) |  |  |
  Unknown | 294 (70.0) |  |  |  |  |
 Relapse |  |  |  |  |  |
  No | 123 (29.3) | 50 (40.7) | 73 (59.3) | 15.991 | 0.000* |
  Yes | 141 (33.6) | 92 (65.2) | 49 (34.8) |  |  |
 Unknown | 156 (37.1) |  |  |  |  |
 Death |  |  |  | 9.151 | 0.002* |
  No | 182 (43.3) | 94(51.6) | 88(48.4) |  |  |
  Yes | 142 (33.8) | 97(68.3) | 45(31.7) |  |  |
 Unknown | 96 (22.9) |  |  |  |  |