Fig. 1

SOX17 immunoreactivity in OCCC cells. SOX17 immunoreactivity was not diffusely but heterogeneously distributed in OCCC cells. Representative staining of diminished SOX17 expression (a). In SOX17-high cases, SOX17 immunoreactivity was focally found in OCCC cells at various intensities (b and c). Intermittent SOX17 immunoreactivity is shown (b) (arrow indicate the SOX17 immunoreactivity). Intratumoral heterogeneous SOX17 immunoreactivity was found in (c) (arrow indicates weak immunoreactivity, while arrowhead indicates strong reactivity). Scale bar, 50 μm