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Fig. 1 | Journal of Ovarian Research

Fig. 1

From: Subtype-specific analysis of gene co-expression networks and immune cell profiling reveals high grade serous ovarian cancer subtype linkage to variable immune microenvironment

Fig. 1

Volcano Plots of DESEQ2 Comparisons ordered by best to worse clinical prognosis. These are estimates of the log2 fold changes (LFC) between conditions, (A) Differentiated vs. Immunoreactive (B) Proliferative vs. Immunoreactive and (C) Mesenchymal vs. Immunoreactive, for each gene with the top five genes within the criteria box. The analysis includes a total of 394 samples (Differentiated: n = 104, Immunoreactive: n = 82, Mesenchymal: n = 95, Proliferative: n = 113). The volcano plot showed gene expression changes’ magnitude (log2 fold change) and statistical significance (-log10 adjusted p-value). Genes that are significantly differentially expressed having a log2 fold change greater than 1 and FDR < 0.05, BH corrected colored in red. Genes beyond the log fold change restriction but not FDR significant are in green, and grey genes are not significantly changed

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Journal of Ovarian Research

ISSN: 1757-2215

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