Fig. 1
From: Single-cell sequencing reveals PTX3 involvement in ovarian cancer metastasis
Characteristics and protein expression of PTX3 at the single-cell level in OC tissue. (A) UMAP plot showing the clustering of all 66,693 cells, with different colors representing distinct cell subgroups. (B) Heatmap displaying the expression levels of known marker genes in each cell subgroup. (C) Heatmap showing the expression of PTX3 in different cell subgroups. (D) Heatmap demonstrating the expression of PTX3 in tumor cells from primary and metastatic lesions. (E) UMAP used for dimensionality reduction and visualization of tumor cells with high or low PTX3 expression. (F) UMAP plot displaying the patient origins of tumor cells, with different colors representing different samples. (G) Pseudotime trajectory analysis based on PTX3 expression. (H) Prognostic analysis based on PTX3 related gene features. (I) IHC detection of PTX3 expression levels in primary OC lesions and paired peritoneal metastatic lesions. Data are presented as mean ± SD; **** P < 0.0001