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Table 1 The characteristics of patients with ovarian cancer

From: Correction: In vitro drug testing using patient-derived ovarian cancer organoids

Original ID

Sample ID

Cancer type

Age

FIGO stage

Neoadjuvant chemotherapy

Debulking status

Adjuvant chemotherapy

Survival status

BRCA geme status

Organoid culture

Organoid expansion

OvCa-19

HGSC-1

High grade serous

54

IIIC

Not received

Suboptimal

Paclitaxel and carboplatin x 6 cycles, followed by lipodox x12 cycles, then second debulking then paclitaxel and carboplatin x6 cycles

Alive

Wild type

Success

No

OvCa-21

EM-1

Endometrioid

40

IC1

Not received

Optimal

Paclitaxel and carboplatin x 9 cycles

Alive

Unexamined

Failed

-

OvCa-26

MC-1

Mucinous

37

IVB

Not received

Optimal

Paclitaxel and carboplatin x 6 cycles, followed by lipodox x 3 cycles, then gemcitabine and carboplatin x3 cycles

Expired

Unexamined

Success

Yes

OvCa-28

MC-2

Mucinous

66

IIIA

Not received

Optimal

Not received due to acute stroke

Expired

Unexamined

Success

Yes

OvCa-29

HGSC-2

High grade serous

61

IVB

Not received

Suboptimal

Paclitaxel and carboplatin x 4 cycles, followed by interval debulking, then paclitaxel and carboplatin x 6 cycles, then lipodox, carboplatin and bevacizumab x6 cycles

Alive

Wild type

Success

Yes

OvCa-32

HGSC-3

High grade serous

62

IVB

Not received

Suboptimal

Paclitaxel and carboplatin x 4 cycles, followed by interval debulking, then paclitaxel and carboplatin x 6 cycles, then lipodox, carboplatin and bevacizumab x6 cycles

Alive

Wild type

Failed

-

OvCa-33

HGSC-4

High grade serous

41

IIIC

Not received

Suboptimal

Paclitaxel and carboplatin x 6 cycles, then lipodox x 6 cycles

Alive

Mutation

Success

Yes

OvCa-34

MC-3

Mucinous

43

IC1

Not received

Optimal

Paclitaxel and cisplatin x4 cycles, then lipodox and bevacizumab x 5 cycles, then gemcitabine and bevacizumab x 2 cycles, then topotecan x 8 cycles

Expired

Unexamined

Failed

-

OvCa-37

CCSC-1

Carcinosarcoma

61

IIIC

Not received

Optimal

Paclitaxel, carboplatin and bevacizumab x 9 cycles, followed by second debulking, then bevacizumab, paclitaxel and carboplatin x 6 cycles, then lipodox x 3 cycles, then gemcitabine x2 cycles

Expired

Wild type

Success

Yes

OvCa-38

CCC-1

Clear cell

32

IC1

Not received

Optimal

Paclitaxel and carboplatin x 4 cycles

Alive

Unexamined

Success

Yes

OvCa-40

CCC-2

Clear cell

49

IIIC

Bevacizumab, paclitaxel and cisplatin x 3 cycle then paclitaxel and carboplatin x 2 cycle

Suboptimal

Gemcitabine and carboplatin x1 cycle

Expired

Unexamined

Success

Yes

OvCa-41

CCC-3

Clear cell

50

IIIB

Not received

Optimal

Rejected

Expired

Unexamined

Success

Yes

OvCa-42

MC-4

Mucinous

47

IC1

Not received

Optimal

Not received

Alive

Unexamined

Success

Yes

OvCa-43

HGSC-5

High grade serous

55

IIIC

Paclitaxel and carboplatin x 4 cycle

Optimal

Paclitaxel and carboplatin x 2 cycles, followed by lipodox x 3 cycles, then gemcitabine x3 cycle

Expired

Wild type

Success

Yes

OvCa-44

EM-2

Endometrioid

58

IIB

Not received

Suboptimal

Paclitaxel and cisplatin x 6 cycles, then lipodox x 3 cycles, then gemcitabine and cisplatin x2 cycles, followed by secondary optimal debulking, then gemcitabine and cisplatin x2 cycles

Alive

Unexamined

Success

Yes

OvCa-45

HGSC-6

High grade serous

70

IIIC

Not received

Optimal

Paclitaxel and carboplatin x 6 cycles, then lipodox and carboplatin x4 cycles

Alive

Unexamined

Success

No

OvCa-46

MC-5

Mucinous

44

IC1

Not received

Optimal

Not received

Alive

Unexamined

Success

Yes

OvCa-49

HGSC-7

High grade serous

55

IIIC

Paclitaxel and cisplatin x 4 cycle

Optimal

Paclitaxel and carboplatin x 2 cycles, followed by lipodox x 3 cycles, then gemcitabine x3 cycles

Expired

Wild type

Success

Yes

OvCa-50

CCC-4

Clear cell

45

IIIC

Not received

Optimal

Paclitaxel and carboplatin x 1 cycle, then second debulking surgery, followed by lipodox and bevacizumab x 1 cycle, then gemcitabine, carboplatin and bevacizumab x 8 cycles.

Alive

Unexamined

Success

Yes

OvCa-51

CCSC-2

Carcinosarcoma

51

IIIA2

Not received

Optimal

Paclitaxel and cisplatin x 1 cycle, then gemcitabine and paclitaxel x 3 cycles

Expired

Unexamined

Failed

-

OvCa-54

CCC-6

Clear cell

51

IIB

Not received

Optimal

Paclitaxel and cisplatin x 6 cycles

Alive

Unexamined

Success

Yes