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Table 1 Mitochondrial transfer studies in ovarian cancer

From: Unveiling the power of mitochondrial transfer in cancer progression: a perspective in ovarian cancer

Donor cells

Recipient cells

Mechanism

Triggers

Cellular effect

Reference

ovarian cancer cells

ovarian cancer cells

TNTs

hypoxia

ND

[94]

ovarian cancer cells

ovarian cancer cells

TNTs

ND

ND

[96]

ovarian cancer cells

ovarian cancer cells

cell fusion

UPR

invasion

[59]

ovarian cancer cells

ovarian cancer cells

TNTs

macrophage-conditioned media

ND

[36]

endothelial cells

ovarian cancer cells

TNTs

ND

ND

[100]

mesothelial cells

ovarian cancer cells

TNTs

ascites-induced compression

ND

[103]

CA-MSCs

ovarian cancer cells

ND

hypoxia

increased proliferation, chemoresistance, metabolic fitness

[106]

MSCs

ovarian cancer cells

cell fusion

ND

reduced proliferation

[65]

human cardiac fibroblast cells

ovarian cancer cells

isolated mitochondrial transplantation

ND

chemotherapeutic sensitivity

[70]

  1. ND: not defined; UPR: unfolded protein response; CA-MSCs: carcinoma-associated mesenchymal stem cells; MSCs: mesenchymal stem cells