Fig. 1
From: Adipocyte-derived CXCL10 in obesity promotes the migration and invasion of ovarian cancer cells
The dysregulated genes in both obese adipose tissues from humans and mice and ovarian carcinoma. A The volcano plot showed differentially expressed genes (P-value < 0.05 and logFC > 1) in obese or ovarian carcinoma compared to their controls. GSE152991_MUO_MHL showed the differentially expressed genes in white adipose tissue between metabolically unhealthy obese (MUO) and metabolically healthy lean (MHL). GSE152991_MHO_MHL showed the differentially expressed genes in white adipose tissue between metabolically healthy obese (MHO) and metabolically healthy lean (MHL). GSE110729_OB indicated differentially expressed genes in samples with a BMI of 47–68 compared to those with a BMI of 20–23. TCGA_OV indicated differentially expressed genes in ovarian carcinoma compared to normal samples. The Venn plots indicated the shared up-regulated genes in both obese and ovarian carcinomas in humans. B The GO plot shows the GO enrichment analysis for the 127 shared genes. C, D The expression of 24 shared up-regulated genes in both obese and ovarian carcinoma from both humans and mice