Unveiling the link: anti-protein disulfide isomerase A3 autoantibody expression and polycystic ovary syndrome risk in euthyroid autoimmune thyroiditis women

Table 4 Binary logistic regression analysis of the potential risk factors for PCOS without PDIA3Ab included among the euthyroid women with AIT

	Model 1 OR (95%CI)	P	Model 2 OR (95%CI)	P	Model 3 OR (95%CI)	P
Age, years	0.958(0.89–1.022)	0.190	0.955(0.895–1.020)	0.169	0.943(0.879–1.012)	0.105
BMI, kg/m²	ND	ND	1.062(0.971–1.161)	0.189	1.061 (0.962–1.171)	0.236
FT4, pmol/L	ND	ND	ND	ND	0.867(0.665–1.132)	0.294
FT3, pmol/L	ND	ND	ND	ND	1.362(0.640–2.899)	0.423
TSH, mIU/L	ND	ND	ND	ND	0.910(0.725–1.120)	0.349
TPOAb, IU/mL	ND	ND	ND	ND	1.001(0.999–1.002)	0.393
TgAb, IU/mL	ND	ND	ND	ND	0.999(0.998–1.001)	0.482

In model 1, only age was included for analysis
In model 2, age, and BMI were included for analysis
In model 3, all those potential risk factors were included, which consisted of age, BMI as well as serum levels of FT4, FT3, TSH, TPOAb, and TgAb
ND, not done in this model
PDIA3Ab: protein disulfide isomerase autoantibody; AIT: autoimmune thyroiditis; PCOS: polycystic ovary syndrome; BMI: body mass index; FT4: free T4; FT3: free T3; TSH: thyroid stimulating hormone; TPOAb: anti-thyroid peroxidase autoantibody; TgAb: anti-thyroglobulin autoantibody

ISSN: 1757-2215