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Table 2 Expression profile of bile acid metabolites in FF from the NOR and DOR groups

From: Bile acids in follicular fluid: potential new therapeutic targets and predictive markers for women with diminished ovarian reserve

Bile Acid Metabolites (nmol/L)

NOR (n = 91)

DOR (n = 91)

P value

 

LCA

86.89 ± 3.59

24.36 ± 1.32

< 0.001*

 

CDCA

361.58 ± 31.96

106.99 ± 10.86

< 0.001*

 

UDCA

141.15 ± 16.50

32.88 ± 4.71

< 0.001*

 

DCA

740.80 ± 69.16

351.24 ± 40.41

< 0.001*

 

CA

197.37 ± 24.54

111.44 ± 17.07

< 0.001*

 

GCDCA

782.61 ± 47.55

654.21 ± 36.65

0.099

 

GUDCA

357.90 ± 39.32

241.34 ± 27.76

0.100

 

TLCA

6.07 ± 0.71

4.96 ± 0.59

0.395

 

GCA

147.85 ± 12.44

173.16 ± 6.99

0.419

 

GDCA

585.96 ± 71.60

561.92 ± 48.95

0.419

 

GLCA

47.21 ± 6.26

43.36 ± 6.06

0.577

 

TCDCA

45.88 ± 3.14

45.81 ± 3.73

0.747

 

THDCA

2.75 ± 0.19

2.75 ± 0.22

0.747

 

TCA

18.17 ± 1.69

20.99 ± 3.00

0.864

 

TDCA

26.71 ± 1.71

27.99 ± 2.10

0.911

 

TUDCA

13.36 ± 0.86

13.99 ± 1.05

0.911

 
  1. Note Continuous data are reported as the mean ± standard deviation. The Mann‒Whitney U test was used to analyze continuous data. NOR = normal ovarian reserve; DOR = diminished ovarian reserve. * P < 0.05