Mechanisms of He Shi Yu Lin formula in treating premature ovarian insufficiency: insights from network pharmacology and animal experiments

Table 2 Receptors and ligands in docking

MOL_ID	PDB ID	molecule_name	OB	MW	DL	Targets	Score kcal/mol
MOL009500	1byq	1,6-dihydroxy-5-methoxy-2-(methoxymethyl)-9,10-anthraquinone	104.54	314.31	0.34	HSP90AA1	-7.5
MOL000392	1jnm	formononetin	69.68	268.28	0.21	JUN	-7.1
MOL004328	2zoq	naringenin	59.29	272.27	0.21	MAPK3	-8.7
MOL000497	6njs	licochalcone A	40.79	338.43	0.28	STAT3	-6.6
MOL000098	1aie	quercetin	46.43	302.25	0.28	TP53	-6.5

PDB Protein Data Bank, OB oral bioavailability, MW molecular weight, DL drug-likeness, JUN jun proto-oncogene, MAPK3 mitogen-activated protein kinase 3, HSP90AA1 heat shock protein 90 alpha family class A member 1, STAT3 signal transduction and activator of transcription, TP53 tumor protein P53

ISSN: 1757-2215