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Table 1 Clinical characteristics of infertile patients with endometriosis and controls in FET cycles

From: Extracellular vesicles-derived MicroRNA-145-5p is upregulated in the uterine fluid of women with endometriosis and impedes mouse and human blastocyst development

Variable

Controls

(n = 30)

Endometriosis

(n = 30)

P values

Female age (years)

34.2 ± 6.1

33.5 ± 5.3

NS

BMI (kg/m2)

22.3 ± 2.4

21.6 ± 2.6

NS

Duration of infertility (years)

4.5 ± 3.1

4.9 ± 3.7

NS

Basal FSH (mIU/mL)

7.7 ± 2.3

8.5 ± 3.2

NS

AMH (ng/mL)

4.31 ± 2.38

3.89 ± 1.62

NS

Oestradiol (pg/mL)

31. 28 ± 8.83

34.91 ± 9.75

NS

Progesterone (ng/mL)

0.83 ± 0.47

0.76 ± 0.46

NS

LH (IU/L)

4.03 ± 1.06

4.39 ± 1.57

NS

Proportion of IVF (%)

18 (60.0)

19 (63.3)

NS

Proportion of ICSI (%)

12 (40.0)

11 (36.7)

NS

Endometrial thickness (mm)

10.3 ± 2.4

9.8 ± 2.5

NS

Embryo transfer cycles (%)

   

 Natural cycles (NC)

33.3% (10/30)

30.0% (9/30)

NS

 HRT cycles

66.7% (20/30)

70.0% (21/30)

NS

Embryo stage (%)

   

 cleavage

13.9% (5/36)

15.4% (6/39)

NS

 blastocyst

86.1% (31/36)

84.6% (33/39)

NS

Thawed embryo survival rates (%)

100% (36/36)

100% (39/39)

NS

No. of transferred embryos

1.2 ± 0.6

1.3 ± 0.7

NS

Implantation rate (%)

36.1 (13/36)

23.1 (9/39)

< 0.01

Clinical pregnancy rate (%)

63.3 (19/30)

36.7 (11/30)

< 0.01

  1. The controls were healthy patients without endometriosis undergoing treatment for tubal factor infertility. FET, Frozen embryo transfer. NS, no significant difference. P values: Unpaired t-test. BMI, body mass index; FSH, follicle-stimulating hormone; IVF, in vitro fertilisation; ICSI, intracytoplasmic sperm injection; HRT, hormone replacement therapy