Extracellular vesicles-derived MicroRNA-145-5p is upregulated in the uterine fluid of women with endometriosis and impedes mouse and human blastocyst development

Table 2 MicroRNAs with high expression levels, identified by miRNA array, between uterine fluid samples from control patients and patients with endometriosis

MicroRNAs	Endometriosis			Controls			FC
MicroRNAs	Raw Ct	ΔCt	RQ	Raw Ct	ΔCt	RQ	FC
hsa-miR-145-5p	23.0494	4.7841	36.2948	26.1280	7.2737	6.4625	5.6162
hsa-miR-720	26.7546	8.4893	2.7827	29.7631	10.9088	0.5201	5.3503
hsa-miR-106b	25.2551	6.9898	7.8678	28.8026	9.9483	1.0122	7.7729
hsa-miR-143	22.2295	3.9642	64.0722	25.9785	7.1242	7.1681	8.9385
hsa-miR-708	22.8780	4.6127	40.8724	26.6919	7.8376	4.3717	9.3493
hsa-miR-486	23.5726	5.6287	5.4628	28.1158	3.2579	67.3218	3.7251
hsa-miR-191	24.9304	6.6651	9.8539	27.0046	8.1503	3.5198	2.7996
hsa-miR-302b	26.6159	8.3506	3.0635	29.0073	10.1530	0.8783	3.4880
hsa-miR-21	26.2200	7.9547	4.0308	24.8751	6.0208	15.4013	0.2617
hsa-miR-146a	21.3511	3.0858	117.7844	20.1410	1.2867	409.8875	0.2874
hsa-miR-378	29.5752	11.3099	0.3939	23.8004	4.9461	32.4396	0.0121
hsa-miR-126	26.2015	7.9362	4.0828	24.1393	5.2850	25.6482	0.1592
hsa-miR-663	25.9662	7.7009	4.8063	21.7182	2.8639	137.3663	0.0350
hsa-miR-451	24.7608	6.4955	11.0828	22.7280	3.8737	68.2182	0.1625
hsa-miR-3600	27.0926	8.8273	2.2015	21.9041	3.0498	120.7588	0.0182
hsa-miR-125a	28.6388	10.3735	0.7538	26.9847	8.1304	3.5687	0.2112
hsa-miR-205	25.8876	7.6223	5.0752	24.0209	5.1666	27.8419	0.1823

Internal reference: snRNA U6. ΔCT = Raw Ct (miRNA)-Raw Ct(U6). Inclusion criteria: Raw Ct < 30. Fold Change (FC) = RQ (Endometriosis)/RQ (Controls), FC > 2 or FC < 0.3, RQ, relative quantity, RQ = 2 ^−ΔCt *1000

ISSN: 1757-2215