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Fig. 2 | Journal of Ovarian Research

Fig. 2

From: Interference with CHD1L inhibits the malignant progression and enhances cisplatin sensitivity of ovarian cancer cells by binding PLK1

Fig. 2

Interference with CHD1L inhibited the proliferation, promoted the apoptosis and induced cycle arrest in OC cells. siRNA-CHD1L was transfected into CAOV-3 cells and the transfection efficiency was detected using RT-qPCR (A) and western blot (B). C. CCK8 assay detected the proliferation of CAOV-3 cells transfected with siRNA-CHD1L. D. EDU staining detected the proliferation of CAOV-3 cells transfected with siRNA-CHD1L. E. TUNEL assay detected the apoptosis of CAOV-3 cells transfected with siRNA-CHD1L. F. Western blot detected the expression of apoptosis-related proteins Bcl-2, Bax, Cleaved caspase3 and caspase3 in CAOV-3 cells transfected with siRNA-CHD1L. G. Cycle distribution of CAOV-3 cells transfected with siRNA-CHD1L was determined by flow cytometry. H. Western blot detected the expression of cycle-related proteins CDK1 and CyclinB1 in CAOV-3 cells transfected with siRNA-CHD1L. **P < 0.01, ***P < 0.001

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Journal of Ovarian Research

ISSN: 1757-2215

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