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Fig. 5 | Journal of Ovarian Research

Fig. 5

From: Interference with CHD1L inhibits the malignant progression and enhances cisplatin sensitivity of ovarian cancer cells by binding PLK1

Fig. 5

Interference with CHD1L inhibited PLK1 expression in OC cells. The (A) BioGrid database, (B) hitpredict database and (C) HDOCK showed that CHD1L could combine with PLK1. D. PLK1 expression in human OC tissues (n = 374) and normal ovarian tissues (n = 133) was analyzed using TNMPLOT database. RT-qPCR (E) and Western blot (F) detected the expression of PLK1 in OC cell lines OVCAR3, CAOV-3 and SCOV3. G. Western blot detected the expression of PLK1 in CAOV-3 cells transfected with siRNA-CHD1L. H. Interaction between CHD1L and PLK1 was analyzed using Co-IP assay. ***P < 0.001

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Journal of Ovarian Research

ISSN: 1757-2215

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