Fig. 3

(a) Representative IHC staining for GROα and MCP-1 in ovarian cancer tissues. Panels A-C: Patient with favorable survival (high-grade serous carcinoma, PFS > 3 years). Panels D-F: Patient with unfavorable survival (clear cell carcinoma, PFS < 1 year). A and D: H&E staining. B and E: GROα staining, predominantly in stromal fibroblasts (thin arrows) with minimal expression in tumor cells (bold arrows). C and F: MCP-1 staining. (b) Kaplan-Meier curves for progression-free survival of the 19 TMA cases, stratified by IHC marker expression. (A) MCP-1 expression in tumor cells. (B) GROα expression in tumor cells. (C) GROα expression in fibroblasts