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Fig. 7 | Journal of Ovarian Research

Fig. 7

From: Long non-coding RNA NEAT1 promotes ovarian granulosa cell proliferation and cell cycle progression via the miR-29a-3p/IGF1 axis

Fig. 7

Regulatory model of the NEAT1/miR-29a-3p/IGF1 axis in KGN cells. NEAT1 functions as a ceRNA by sponging miR-29a-3p, thereby preventing miR-29a-3p-mediated suppression of IGF1 mRNA translation. This regulation promotes IGF1 expression, which in turn enhances cell proliferation and cell cycle progression by upregulating cell cycle-related proteins CCNB1 and CDK2

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Journal of Ovarian Research

ISSN: 1757-2215

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