Fig. 2

Collection of S. rubriflora’s targets in PCOS treatment. A Differential expression genes (DEGs) in peripheral blood samples of PCOS patients and control subjects were screened with P < 0.05, |log2 fold change|>1 as the threshold. The horizontal axis is the multiple change in gene expression, and the vertical axis is the statistical significance (p-value) of the change in gene expression. Pink dots represent up-regulated genes and green dots represent down-regulated genes. B Venn diagram of the targets of S. rubriflora’s ingredients and the DEGs associated with PCOS. C Stratified clustering heat maps of the targets of S. rubriflora in PCOS treatment