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Table 2 Comparison of ovarian stimulation parameters between two treatment protocols before and after propensity score matching

From: Pretreatment with oral contraceptives benefit POSEIDON group 1 low prognosis patients during GnRH-antagonist protocol: a propensity score-matched retrospective cohort study

Variable

Before matching

After matching

OCs

(n = 401)

non-OCs

(n = 1821)

P value

OCs

(n = 369)

non-OCs

(n = 879)

P value

Total Gn dose (IU)

2695.92±

939.72

2674.20±

1082.84

0.927

2762.84±

931.77

2820.93±

1025.72

0.590

Duration of Gn (days)

9.66 ± 2.09

9.40 ± 2.53

0.053

9.64 ± 2.13

9.89 ± 2.30

0.077

E2 levels at the day of hCG (pg/ml)

2282.13±

1097.80

1618.97±

1173.90

0.*

2250.24±

1094.11

1878.22±

1199.37

0.*

LH levels at the day of hCG (IU/L)

2.33 ± 2.69

3.56 ± 4.91

0.*

2.42 ± 2.79

3.06 ± 3.61

0.*

P levels at the day of hCG (mg/ml)

0.90 ± 0.43

0.85 ± 0.47

0.017*

0.91 ± 0.43

0.90 ± 0.48

0.659

Follicles ≥ 14 mm at day of hCG (n)

6.76 ± 3.73

4.73 ± 3.32

0.*

6.52 ± 3.67

5.59 ± 3.29

0.*

Endometrial thickness (mm)

10.31 ± 2.38

10.42 ± 2.69

0.775

10.25 ± 2.37

10.85 ± 2.68

0.*

No. of oocytes retrieved (n)

5.85 ± 2.26

4.45 ± 2.69

0.*

5.77 ± 2.25

5.06 ± 2.50

0.001*

No. of 2PN (n)

3.64 ± 2.05

2.70 ± 2.13

0.*

3.52 ± 2.02

3.00 ± 2.07

0.*

Available embryos (n)

3.83 ± 2.85

2.04 ± 2.17

0.*

3.75 ± 2.04

3.21 ± 2.10

0.*

Good quality embryos (n)

1.65 ± 1.48

1.21 ± 1.39

0.*

1.60 ± 1.45

1.34 ± 1.39

0.*

OSI

2.53 ± 1.56

1.79 ± 1.31

0.*

2.40 ± 1.49

1.97 ± 1.28

0.*

  1. All values presented as mean ± SD or n (%)
  2. OCs, oral contraceptives; Gn, gonadotropin; E2, estrogen; LH, luteinizing hormone; P, progesterone; FORT, follicular output rate; PN, pronucleus; OSI, ovarian sensitivity index
  3. * indicates statistically significant of P<0.05