Table 1 The causal relationship between metabolic syndrome and ovarian dysfunction using mendelian randomization

79

1.01 ( 0.71–1.43 )

0.97

1.24 ( 0.59–2.57 )

0.57

1.07 ( 0.63–1.82 )

0.81

1.32 ( 0.54–3.18 )

0.54

299

1.66 ( 0.81–3.41 )

0.17

1.37 ( 0.17–11.19 )

0.77

1.11 ( 0.37–3.37 )

0.85

0.32 ( 0.04–2.68 )

0.29

432

1.25 ( 0.72–2.14 )

0.43

0.67 ( 0.15–3 )

0.60

1.45 ( 0.6–3.53 )

0.41

1.13 ( 0.2–6.34 )

0.89

18

0.26 ( 0.08–0.89 )

0.03

2.83 ( 0.14–58.73 )

0.51

0.22 ( 0.04–1.26 )

0.09

0.06 ( 0–1.39 )

0.10

63

0.5 ( 0.17–1.54 )

0.23

0.48 ( 0.07–3.56 )

0.48

0.48 ( 0.1–2.46 )

0.38

0.42 ( 0.09–2.1 )

0.3

86

1.33 ( 0.86–2.07 )

0.2

1.52 ( 0.74–3.12 )

0.25

1.87 ( 0.92–3.79 )

0.08

1.55 ( 0.86–2.8 )

0.15

54

1.14 ( 0.62–2.07 )

0.67

0.93 ( 0.35–2.5 )

0.89

0.74 ( 0.3–1.79 )

0.5

0.83 ( 0.38–1.8 )

0.64

81

1.11 ( 0.92–1.34 )

0.29

0.82 ( 0.56–1.21 )

0.33

1.06 ( 0.81–1.4 )

0.68

1.03 ( 0.71–1.49 )

0.88

299

2.14 ( 1.45–3.15 )

< 0.001

4.54 ( 1.48–13.9 )

0.01

1.91 ( 1.06–3.46 )

0.03

0.76 ( 0.16–3.67 )

0.74

432

2.1 ( 1.56–2.83 )

< 0.001

3.06 ( 1.34–6.99 )

0.01

2.35 ( 1.48–3.71 )

< 0.001

5.34 ( 1.63–17.51 )

0.01

18

1.16 ( 0.61–2.23 )

0.65

3.36 ( 0.67–16.71 )

0.16

1.3 ( 0.54–3.1 )

0.56

1.16 ( 0.3–4.44 )

0.83

63

1.74 ( 0.97–3.13 )

0.06

1.87 ( 0.65–5.35 )

0.25

1.19 ( 0.45–3.12 )

0.72

0.83 ( 0.28–2.46 )

0.74

86

1.2 ( 0.96–1.52 )

0.12

1.5 ( 1.03–2.19 )

0.04

1.53 ( 1.03–2.27 )

0.04

1.46 ( 1.03–2.07 )

0.04

54

1.01 ( 0.75–1.37 )

0.94

0.74 ( 0.45–1.21 )

0.24

0.89 ( 0.57–1.4 )

0.62

0.86 ( 0.57–1.29 )

0.47