miR-34a-5p modulation of polycystic ovary syndrome via targeting the NOTCH signaling pathway

Table 3 Anthropometric and metabolic parameters of all participants

Characteristics	NC (n = 20)	PCOS (n = 19)	P value
Age	33. 75 ± 3. 007	33. 95 ± 4. 428	0. 8709
BMI (kg/m²)	20. 80 ± 1. 737	24. 36 ± 3. 443	0. 0002 ***
WHR	0. 8269 ± 0. 04297	0. 8732 ± 0. 05774	0. 0062 **
SBP (mmHg)	117. 2 ± 7. 63	121. 1 ± 11. 49	0. 2229
DBP (mmHg)	70. 65 ± 5. 55	78. 32 ± 11. 50	0. 0111 *
FPG (mmol/L)	4. 67 ± 0. 27	4. 85 ± 0. 30	0. 0451 *
FINS (mIU/L)	7. 71 ± 1. 75	10. 85 ± 4. 60	0. 0071 **
HOMA-IR	0. 1655 ± 50. 04006	0. 2337 ± 0. 09702	0. 0063 **
TC(mmol/L)	4. 643 ± 0. 579	4. 856 ± 1. 048	0. 4201
TG(mmol/L)	0. 8000 ± 0. 2547	1. 452 ± 1. 185	0. 0214 *
HDL(mmol/L)	1. 607 ± 0. 2247	1. 433 ± 0. 2849	0. 0401 *
LDL(mmol/L)	2. 751 ± 0. 4479	2. 626 ± 0. 8709	0. 5760
FSH (mIU/mL)	7. 410 ± 1. 163	5. 636 ± 0. 9047	< 0. 0001 *****
LH (mIU/mL)	5. 608 ± 1. 875	7. 632 ± 3. 216	0. 0207 *
E2(PG/mL)	223. 3 ± 159. 9	191. 9 ± 190. 9	0. 5805
P (nmol/L)	1. 613 ± 3. 862	2. 075 ± 5. 464	0. 7633
T (nmol/L)	0. 6195 ± 0. 1855	1. 222 ± 0. 4499	< 0. 0001 ****
LH/FSH	0. 7945 ± 0. 3530	1. 375 ± 0. 5618	0. 0004 ***
AFC	15. 75 ± 8. 039	34. 11 ± 12. 83	< 0. 0001 ****

Data are presented as mean ± SD
BMI, body mass index; WHR, waist-to-hipratio; SBP, systolic blood pressure; DBP, diastolic blood pressure; FPG, fasting plasma glucose; FINS, fasting plasma insulin; HOMA-IR, homeostasis model assessment of insulin resistance; TC, total cholesterol; TG, triglyceride; HDL, high-density plasma insulin; HOMA-IR, homeostasis model assessment of insulin resistance; TC, total cholesterol; TG, triglyceride; high-density lipoprotein; LDL, low-density lipoprotein; FSH, follicular stimulating hormone; LH, luteinising hormone; E2, estradiol; P, progesterone; T, testosterone; AFC, antral follicle count

ISSN: 1757-2215