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Table 1 Comparison of baseline and reproductive characteristics of the difference between primary and secondary infertile groups

From: Association of age at menarche and different causes of infertility: a retrospective study of 7634 women undergoing assisted reproductive technology

 

Primary infertility

(N = 4378)

Secondary infertility

(N = 3265)

P value

Age at time of study (years)

28.00 (26.00, 31.00)

34.00 (30.00, 38.00)

< 0.001***

BMI at time of study (kg/m^2)

22.56 (20.44, 25.36)

23.59 (21.48, 25.98)

< 0.001***

Age at menarche (years)

14.00 (13.00, 15.00)

14.00 (13.00, 15.00)

< 0.001***

AAM category n (%)

 ≤12

658 (15.0)

351 (10.8)

< 0.001***

 13

1105 (25.2)

734 (22.5)

 

 14

1203 (27.5)

889 (27.2)

 

 15

794 (18.1)

661 (20.2)

 

 16

439 (10.0)

397 (12.2)

 

 ≥ 17

179 (4.1)

233 (7.1)

 

Educational level n (%)

   

 Primary school and below

171 (3.9)

247 (7.6)

< 0.001***

 Middle school

1402 (32.0)

1293 (39.6)

 

 High school or technical secondary school

949 (21.7)

724 (22.2)

 

 Junior college degree

905 (20.7)

423 (13.0)

 

 Bachelor’s degree

775 (17.7)

530 (16.2)

 

 Master’s degree and above

176 (4.0)

48 (1.5)

 

Irregular menstruation n (%)

 No

3402 (77.7)

2763 (84.6)

< 0.001***

 Yes

976 (22.3)

502 (15.4)

 

Dysmenorrhea n (%)

   

 No

3751 (85.7)

2951 (90.4)

< 0.001***

 Yes

627 (14.3)

314 (9.6)

 

Family history (Whether mother had infertility) n (%)

 No

4304 (98.3)

3220 (98.7)

0.276

 Yes

74 (1.7)

45 (1.3)

 

Cause of infertility n (%)

   

 PCOS

486 (11.1)

149 (4.6)

< 0.001***

 Endometriosis

90 (2.1)

61 (1.9)

 

 DOR

99 (2.3)

76 (2.3)

 

 Unexplained infertility

190 (4.3)

113 (3.5)

 

 Tubal factor

3513 (80.2)

2866 (87.8)

 
  1. Notes: *** Primary infertility group vs. Secondary infertility group, P < 0.001
  2. Abbreviations: BMI, body mass index; AAM, age at menarche; PCOS, polycystic ovary syndrome; DOR, diminished ovarian reserve