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Table 4 Multivariate regression models for AAM and risk of different causes of infertile groups

From: Association of age at menarche and different causes of infertility: a retrospective study of 7634 women undergoing assisted reproductive technology

 

Age at menarche

Per + 1 year age at menarche

≤ 12

13

14

15

16

≥ 17

OR (95%CI)

P

OR (95%CI)

P

Ref

OR (95%CI)

P

OR (95%CI)

P

OR (95%CI)

P

OR (95%CI)

P

PCOS

             

Rude

1.025 (0.766, 1.371)

0.868

1.143 (0.902, 1.447)

0.268

1.00

1.262 (0.989, 1.611)

0.061

1.389 (1.049, 1.840)

0.022

1.602 (1.129, 2.272)

0.008

1.083 (1.025, 1.114)

0.005

Adjusted

0.879 (0.650, 1.189)

0.404

1.086 (0.851, 1.385)

0.508

1.00

1.393 (1.082, 1.792)

0.010

1.619 (1.207, 2.171)

0.001

2.346 (1.625, 3.389)

< 0.001

1.176 (1.109, 1.247)

< 0.001

Endometriosis

             

Rude

1.572 (0.974, 2.535)

0.064

1.066 (0.680, 1.671)

0.780

1.00

0.892 (0.540, 1.475)

0.656

0.812 (0.432, 1.525)

0.517

0.650 (0.255, 1.656)

0.367

0.865 (0.771, 0.971)

0.014

Adjusted

1.446 (0.891, 2.348)

0.135

1.043 (0.664, 1.638)

0.854

1.00

0.917 (0.554, 1.518)

0.736

0.852 (0.451, 1.608)

0.621

0.676 (0.263, 1.735)

0.416

0.889 (0.790, 1.002)

0.053

DOR

             

Rude

2.608 (1.571, 4.330)

< 0.001

2.996 (1.924, 4.664)

< 0.001

1.00

1.045 (0.586, 1.864)

0.881

1.280 (0.670, 2.447)

0.454

1.522 (0.688, 3.369)

0.300

0.789 (0.707, 0.880)

< 0.001

Adjusted

2.565 (1.535, 4.287)

< 0.001

3.026 (1.940, 4.720)

< 0.001

1.00

1.031 (0.577, 1.843)

0.917

1.261 (0.657, 2.422)

0.486

1.410 (0.632, 3.146)

0.402

0.786 (0.701, 0.880)

< 0.001

Unexplained

infertility

             

Rude

1.036 (0.707, 1.518)

0.855

1.001 (0.726, 1.380)

0.997

1.00

0.998 (0.709, 1.405)

0.992

0.874 (0.568, 1.344)

0.539

1.128 (0.670, 1.901)

0.650

0.994 (0.918, 1.076)

0.877

Adjusted

0.960 (0.652, 1.414)

0.836

0.992 (0.719, 1.370)

0.963

1.00

1.023 (0.725, 1.441)

0.899

0.926 (0.599, 1.430)

0.728

1.183 (0.697, 2.009)

0.534

1.019 (0.938, 1.106)

0.713

  1. Notes: Adjusted for age at time of study, BMI at time of study, educational level, family history and different types of infertility
  2. Abbreviations: AAM, age at menarche; BMI, body mass index; PCOS, polycystic ovary syndrome; DOR, diminished ovarian reserve