Table 3 Tests for heterogeneity and Pleiotropy
Exposure ID | Outcome | Heterogeneity | Pleiotropy | ||||||
|---|---|---|---|---|---|---|---|---|---|
MR Egger | Inverse variance weighted | Egger intercept | SE | Pval | MR-PRESSO Global | ||||
Statistics Q | P-Value | Statistics Q | P-Value | Pval | |||||
family.Victivallaceae.id.2255 | OC | 6.269 | 0.792 | 7.482 | 0.759 | 0.030 | 0.028 | 0.297 | 0.773 |
genus.ChristensenellaceaeR.7group.id.11,283 | OC | 11.822 | 0.224 | 14.591 | 0.148 | 0.029 | 0.020 | 0.181 | 0.174 |
genus.Escherichia.Shigella.id.3504 | OC | 7.828 | 0.855 | 8.116 | 0.883 | -0.008 | 0.014 | 0.600 | 0.868 |
genus.FamilyXIIIAD3011group.id.11,293 | OC | 9.115 | 0.693 | 9.668 | 0.721 | 0.020 | 0.026 | 0.471 | 0.758 |
genus.Prevotella9.id.11,183 | OC | 11.305 | 0.731 | 13.832 | 0.611 | -0.019 | 0.012 | 0.133 | 0.645 |
genus.Tyzzerella3.id.11,335 | OC | 7.582 | 0.750 | 7.633 | 0.813 | 0.007 | 0.032 | 0.827 | 0.820 |
genus.unknowngenus.id.2041 | OC | 7.666 | 0.467 | 8.384 | 0.496 | -0.014 | 0.016 | 0.422 | 0.509 |
genus.unknowngenus.id.2071 | OC | 16.662 | 0.339 | 17.100 | 0.379 | -0.016 | 0.025 | 0.540 | 0.402 |
phylum.Euryarchaeota.id.55 | OC | 10.916 | 0.450 | 12.219 | 0.428 | -0.025 | 0.022 | 0.278 | 0.437 |
class.Erysipelotrichia.id.2147 | EC | 5.778 | 0.888 | 7.793 | 0.801 | 0.034 | 0.024 | 0.183 | 0.807 |
family.Erysipelotrichaceae.id.2149 | EC | 5.778 | 0.888 | 7.793 | 0.801 | 0.034 | 0.024 | 0.183 | 0.819 |
family.FamilyXI.id.1936 | EC | 6.992 | 0.537 | 7.796 | 0.555 | -0.026 | 0.029 | 0.396 | 0.590 |
genus.Dorea.id.1997 | EC | 12.422 | 0.333 | 12.527 | 0.404 | 0.006 | 0.018 | 0.767 | 0.416 |
genus.RuminococcaceaeUCG014.id.11,371 | EC | 14.383 | 0.570 | 14.383 | 0.640 | 1.0E-04 | 0.015 | 0.995 | 0.665 |
genus.Turicibacter.id.2162 | EC | 10.369 | 0.584 | 10.787 | 0.629 | 0.015 | 0.023 | 0.530 | 0.644 |
order.Erysipelotrichales.id.2148 | EC | 5.778 | 0.888 | 7.793 | 0.801 | 0.034 | 0.024 | 0.183 | 0.812 |