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Table 4 Morphometric analysis of ovarian weight histology, values represent the mean ± sem of 6 groups

From: Ameliorative effect of Fagonia indica-coated chitosan nanoparticles on the ovulatory pattern in PCOS rat model

Parameters

NC

PCOS

Metformin

F. indica

(500 mg/kg)

FICNPs

(50 mg/kg)

FICNPs

(100 mg/kg)

Ovarian Weight(g)

0.15e ± 0.01

0.26b ± 0.02

0.14e ± 0.01

0.16e ± 0.01

0.17e ± 0.01

0.13e ± 0.01

Granulosa cells

0.01e ± 0.00

0.05a ± 0.00

0.01e ± 0.00

0.04b ± 0.00

0.04b ± 0.00

0.02d ± 0.00

Oocyte

0.02c ± 0.00

0.19a ± 0.05

0.00c ± 0.00

0.16ab ± 0.01

0.135ab ± 0.065

0.08bc ± 0.02

Antral Diameter

0.02e ± 0.00

0.24a ± 0.02

0.03e ± 0.00

0.11cde ± 0.00

0.03e ± 0.00

0.07e ± 0.01

No of cystic follicles

1.20e ± 0.20

8.50a ± 0.43

2.17e ± 0.31

2.76cde ± 0.36

2.83b ± 0.47

2.18ab ± 0.37

No of corpus luteum

5.40 ± 0.51cd

2.33 ± 0.33a

4.9 ± 0.37d

4.14 ± 0.40ab

4.16 ± 0.60bc

4.80 ± 0.37bc

No of healthy follicles

10.40 ± 0.50C

4.17 ± 0.48a

9.50 ± 0.62c

6.29 ± 0.42a

6.33 ± 0.42b

8.20 ± 0.58b

  1. Note: a−e Within the same row, means with different superscripts are significantly different (p < 0.05)