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Table 4 Perinatal outcomes of control and four phenotypes of PCOS patients giving birth to singletons after the frozen-thawed embryo transfers

From: Enhancing understanding of endometrial function in patients with PCOS: clinical and immunological insights

Variable

Women without PCOS (n = 5994)

Women with PCOS (n = 717)

 

PCOM + HA + OA (n = 452)

P value

PCOM + HA(n = 50)

P value

PCOM + OA(n = 206)

P value

HA + OA (n = 9)

P value

Gestational age, weeks

39.0 (38.1, 39.6)

39.0 (38.0, 39.6)

0.4511

38.6 (37.4, 39.0)

0.0051*

39.0 (38.3, 39.7)

0.1451

38.7 (38.0, 39.5)

0.6031

Birth weight, g

3350.0 (3100.0, 3650.0)

3350.0 (3100.0, 3650.0)

0.9881

3300.0 (3000.0, 3663.0)

0.5941

3440.0 (3100.0, 3750.0)

0.0631

3600.0 (2950.0, 3950.0)

0.5001

Delivery mode

  

0.3972

 

0.4882

 

0.7632

 

13

 Natural labor

800 (13.3%)

54 (11.9%)

 

5 (10.0%)

 

29 (14.1%)

 

1 (11.1%)

 

 Cesarean delivery

5193 (86.7%)

398 (88.1%)

 

45 (90.0%)

 

177 (85.9%)

 

8 (88.9%)

 

Gender

  

0.3762

 

0.4852

 

0.3462

 

0.5273

 Male

3292 (54.9%)

258 (57.1%)

 

25 (50.0%)

 

120 (58.3%)

 

6 (66.7%)

 

 Female

2701 (45.1%)

194 (42.9%)

 

25 (50.0%)

 

86 (41.7%)

 

3 (33.3%)

 

Abnormal perinatal outcomes

         

 VPTB

45 (0.8%)

4 (0.9%)

0.7753

0 (0.0%)

13

1 (0.5%)

13

0 (0.0%)

13

 PTB

497 (8.3%)

44 (9.7%)

0.2882

9 (18.0%)

0.0343*

14 (6.8%)

0.4422

1 (11.1%)

0.5423

 VLBW

27 (0.5%)

2 (0.4%)

13

0 (0.0%)

13

1 (0.5%)

0.6113

0 (0.0%)

13

 LBW

260 (4.3%)

20 (4.4%)

0.9162

1 (2.0%)

0.7243

6 (2.9%)

0.3262

1 (11.1%)

0.3303

 Macrosomia (≥ 4000 g)

375 (6.3%)

35 (7.7%)

0.2032

1 (2.0%)

0.3713

18 (8.7%)

0.1452

1 (11.1%)

0.4423

 VSGA

115 (1.9%)

9 (2.0%)

0.9062

1 (2.0%)

0.6223

4 (1.9%)

0.7993

0 (0.0%)

13

 SGA

207 (3.5%)

19 (4.2%)

0.3952

1 (2.0%)

13

8 (3.9%)

0.7322

0 (0.0%)

13

 LGA

951 (15.9%)

75 (16.6%)

0.6622

8 (16.0%)

0.9822

40 (19.4%)

0.1642

4 (44.4%)

0.0413*

 HDP

234 (3.9%)

25 (5.5%)

0.0892

8 (16.0%)

<.0013*

14 (6.8%)

0.0372*

2 (22.2%)

0.0463*

 GDM

343 (5.7%)

33 (7.3%)

0.1672

7 (14.0%)

0.0243*

8 (3.9%)

0.2612

1 (11.1%)

0.4123

 Fetal malformation

62 (1.0%)

10 (2.2%)

0.0222*

1 (2.0%)

0.4093

1 (0.5%)

0.7243

1 (11.1%)

0.0913

  1. 1Mann-Whitney U tests; 2Chi-Square p-value; 3Fisher Exact p-value. Continuous data are reported as the median (quartiles). Categorical data are reported as n (%). PCOS = polycystic ovary syndrome. *P < 0.05