Fig. 7
From: Downregulation of FASN in granulosa cells and its impact on ovulatory dysfunction in PCOS
Effects of 4-week FASN downexpression in rat ovaries mediated by lentivirus vectors. A Body weight of rats(n = 6 per group); B Appearance of the rat ovaries; C Weight of rats(n = 12 per group); D Estrous cycles were detected in rats injected with control vector (above) or FASN lentivirus vector (below)(n = 6 per group); E Serum estradiol(E2)(left) and Progesterone(right) levels detected by ELISA analysis(n = 6 per group); F Ovarian morphology of rats injected with control vector (above) or FASN lentivirus vector (below). Asterisk stands for corpus luteum. Scale bar, 1000 μm. Data were analyzed using unpaired samples t-test and are presented as mean ± SEM. *P < 0.05, **P < 0.01, **P < 0.001 vs. the control group